I have a history of IBS and have avoided gluten and used probiotics which has helped my GI tract to return to normal. Keep a diet diary for 4-5 days and you should be able to easily see how much calcium your diet is providing for you. However, you must take Strontium either without food or if with a meal, it should be a meal that does not contain calcium. This study was done to see how much strontium this osteoporotic womans bones were absorbing from a strontium citrate supplement (680 mg elemental strontium per day) and whether the beneficial effect continued after 800 days it did. https://www.sciencedaily.com/releases/2008/07/080728081346.htm (actual paper: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.23674) The GAIL score discussed in this paper relates to indicators of a womans lifetime risk for invasive breast cancer. In fact, the bone loss developed at a rapid rate, taking just four weeks to advance to osteopenia, a forerunner to the more severe form of bone loss disease, osteoporosis. The bacteria were not only detectable in the bones of mice, they were seen to cause significant bone loss in the longer bones, mere weeks after infection. Osteoporosis does run in my family with both my grandmother and my mom struggling with this. I had a small fracture in the pelvic area. Do you have any information regarding this product? Hi Kathy, Hi Lara: Here are links to these #AskLara: https://www.facebook.com/lara.pizzorno.5/videos/10220814548543995/ The only negative effect of taking strontium citrate along with a calcium-rich meal is that you will get little, if any, benefit from the strontium. Hello I had a 24 hr clearence test and yhe last one was 72 measure should I take Strontium? Hi Lara: I have been taking Strontium Citrate 680 mg first thing in the morning for several years for osteoporosis.. PMID: 21925296: In animal research, female rats whose ovaries had been removed (the standard protocol used to simulate human menopause) were given strontium chloride over a 2-month period. I know you focus on strontium supplementation but should I be concerned if I have too much strontium? Strontium was dose-dependently incorporated into bone mineral of both trabecular and compact bone, mainly into new bone, and mainly into trabecular boneNo changes in the crystal lattice, in crystallinity, or crystal structure were observed. I take a Progessive MultiVitamin for women over 50 three times a day as suggested. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. Personally, I rely upon both vitamin A, which I take in an amount equivalent to the vitamin D3 I need to take, and 2 tablespoons of Triple Power each day, to keep my inflammation down and to protect not just my bones but my overall health. Epub 2016 Oct 21. AP/SB, as the research shows (3rd study), can turn this around even in postmenopausal women losing at least 2% or more annually. is he board certified, etc.? Try taking 150 mg of magnesium citrate along with one capsule of P-5-P (pyridoxal-5-phosphate) in the evening along with your Strontium Boost. Nonethelss, I believe this may indicate suboptimal vitamin K2 status, plus many studies have now demonstrated that vitamin K (and specifically K2) is needed for healthy bones and to prevent calcification of arteries and other soft tissues. COMPETITION BETWEEN CALCIUM, STRONTIUM, AND MAGNESIUM FOR ABSORPTION IN THE ISOLATED RAT INTESTINE.Clin Chem. Within 3 hours, you will have digested the yogurt and absorbed the calcium in it. We now have evidence that the degree of mineralization of bone tissue strongly influences not only the mechanical resistance of bones but also the bone mineral density. FYI the amount of strontium provided in the full dose is not 682 mg. Strontium Boost is strontium citrate, which is 31% elemental strontium and 69% citrate. You should also avoid taking it with calcium supplements or calcium-rich foods or consuming these foods 2 hours prior or 4 hours after taking the medication because the calcium can decrease the body's ability to absorb the hormone. However, you may have heard some less-than-confidence inspiring things about strontium. From Laras Comment at bottom of: Strontium Side Effects are Overblown Get the Facts: Strontium is almost twice as large as calcium, and its larger size does affect DXA readings. Lara, Thanks for the extra git you gave, much appreciated. You have to let him go!" Maggie was adamant. Hi Debra, How are your kidneys? doi: 10.1136/bmjopen-2014-005787. In other words, whether your bone density increases or not, strontium reduces your risk of breaking a bone! Every woman in my family whom I know about for many generations back died from osteoporosis I am the poster child for risk for this disease, but have managed to beat it by learning what my bones need and supplying it. These findings could reflect dose-dependent stimulation of bone formation and are of potential value for the use of SR in the treatment of osteoporosis. Drastically reduced milk as they say it becomes acidic in the body switching to rice milk, hemp and now almond. Your advice would be much appreciated. Additionally I have been using Doctors Best Strontium. Thanks again for catching my misspelling of Dr. Genuis name and for your really great questions, Lara, Hi Lara, Strontium carbonate notably is found in cathode ray tubes in old television sets. I needs to spend some time learning more or working out more. I plan to do so. There are a number of important to me differences between the algae used in New Chapter Bone Strength Take Care (Aquamin) and that which is used for AlgaeCal (Algas calcareus). http://www.lmreview.com/articles/view/select-the-right-hormone-test-for-your-patient-using-bio-identical-hormone-/ Hope this helps! I think this is good advice especially if the patient has impaired renal function and thus subsequent decrease in its clearance by the kidney. In adult bone, our model is based on the impact of changes in the bone remodeling rate on the degree of mineralization of bone tissue. Sawai Y, Murata H, Koto K, Matsui T, Horie N, Ashihara E, Maekawa T, Fushiki S, Kubo T. Effects of low-intensity pulsed ultrasound on osteosarcoma and cancer cells. That's true whether you have hypothyroidism (low thyroid activity) or hyperthyroidism (high thyroid activity). So would taking a magnesium tablet solve the problem? Again, I want to underscore that strontiums beneficial effects on our bones NOT due to its taking the place of calcium. Women in the Plan 3 group, the group receiving the most nutritionally comprehensive supplement program (the one now available at https://blog.algaecal.com/, gained significantly more BMD than the other two groups. I actually enjoy eating natto this way and look forward to it. (We should take more calcium than strontium in order for both to be effective.) If you have osteopenia or osteoporosis you should take two capsules daily on an empty stomach. I am assuming that the new bone at 2 months is the old bone at 60 months or at least some of it is. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Dialysis fluid can contain high concentrations of strontium, so not surprisingly, some dialysis patients are known to have elevated bone strontium concentrations and a high strontium/calcium ratio in bone. Effect of impact exercise on bone mineral density in elderly women with low BMD: a population-based randomized controlled 30-month intervention, Osteoporosis International, vol. Ive read that estrogens might decrease how fast the body gets rid of strontium and cause side effects. Great! Here it is copied below: Re strontium citrate not specifically being shown in the research: It has been clearly stated in the research that the strontium ions, NOT ranelic acid (ranelate) are what are producing the beneficial effects on bone. Please feel free to contact our Bone Health Consultants 7 days a week at 1-800-820-0184 (USA & Canada, toll-free) or email [emailprotected] for more information and personalized support! I do much better with starchy whole vegetables like potatoes, yams, corn, beets, winter squash. I use AlgaeCal Plus for my supplemental calcium and vitamin K, and part of my vitamin D (I need additional vitamin D because of my genetic inheritance my vitamin D receptors dont work very well, so I need more vit D than most people), and I take Strontium Boost for my strontium. Pilates exercises with an instructor who has been trained to work specifically with people with bone loss may be very helpful for you. One caveat here if you eat tuna PLEASE purchase tuna that has been checked for mercury content! You are so welcome! In addition, the expressions of metabolizing enzymes (CYP3A4/CYP3A9 and UDPG) showed 12 to 193-fold difference between human and rat intestine with distinct regional dependent expression patterns. One very important factor to consider is vitamin A. Vitamin A is the key nutrient required for immune tolerance (vitamin A is involved in causing the immune system to produce regulatory T cells of the IL-10 strain, which help tune down and resolve inflammation), and many of us are not getting adequate vitamin A, which also works in partnership with vitamin D and should be consumed in comparable amounts for the optimal benefits derived from both nutrients. How quickly our kidneys filter creatinine from the bloodstream, which is called the creatinine clearance rate, provides a measure of how effectively your kidneys are filtering your blood. CONCLUSIONS: The data indicate that rat and human show similar drug intestinal absorption profiles and similar transporter expression patterns in the small intestine, while the two species exhibit distinct expression levels and patterns for metabolizing enzymes in the intestine. Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. I wish it were less complicated, and we could all just do exactly the same thing, and it would be just right for each of us but this is not how it is. So are you comfortable with me taking 2 of the AlgaeCal daily as I was hoping to up by strontium to 2 daily. This helps to ensure proper absorption of thyroid hormone and therefore maintain consistent TSH level. Epub 2013 Jul 24. https://www.arthritis.org/about-arthritis/types/calcium-pyrophosphate-deposition-disease-cppd/ A few years ago now, I also started to experience pain in my thumb joints (and sometimes other fingers as well), which would clear out after a few days. (2006 JBMR 21(9) 1417-24, Its also vitally important to recognize that, Strontium Boost: 2 capsules right before bed (on an empty stomach), Activate vitamin D (vitamin D is converted into its active, hormonal form in the kidneys which is the form in which vitamin D helps us absorb calcium from the digestive tract), Re-absorb calcium passing through the kidneys in the bloodstream instead of losing it in urine. Are you able to eat omega-3 rich fish like wild caught salmon or would you consider taking a DHA/EPA supplement? I asked AlgaeCal for a response to your question and it appears that the reason is a legal issue. I am 57-years-old. And stay gloriously well, Both IGF-I and Runx2 levels were positively associated with the bone mineral apposition rate (MAR). is really stellar. I suggest you ask your doctor to run a test to have your vitamin A levels checked, and if they are not well within the normal range, that you consider supplementing with an amount of vitamin A comparable to the amount of vitamin D3 you consume. Actually, no one has asked whether strontium replaces calcium in our bones. Good morning Farah, I have a smoothie for breakfast that contains a bunch of kale. Thank you JoAnn Rice. Hi Antigone, As you know, our bones continue to remodel throughout our lives, so the therapies used to support healthy bones must be ones we can rely on long-term. I found NOF, and actually they did a good job of alarming me. You can get this small amount of MK-4 from foods though a list of food sources is in my vit K2 review on LMR. Bone. It would be very helpful if you could clarify. Happy Thanksgiving to you, too. The study found that the amount of bone loss directly correlated to the bacterial load found in the bones. Since your bones are now in such good shape, however, I suggest you consider using only a half dose (1 capsule of Strontium Boost) daily instead of the full 2 capsule dose. femoral neck] last July, I have been following the Save our Bones programme, taking Raw Calcium, a special over 50 muli- vitamin and other supplements. I use organic extra virgin olive oil and balsamic vinegar for salad dressing. The X-ray microanalysis method provided a semiquantitative evaluation of the amount of strontium taken up by the bone mineral substance, and its localization. I also have my son, daughter and husband taking Triple Power along with me. Finally, plasma total ALP activity and IGF-I were also increased in treated animals, compatible with a bone-forming activity of strontium ranelate. Keep asking questions! If you are taking 7,000 IU vit D3, then this amount of MK-7 should be adequate. My primary care physician started prescribing me the 1mg estradiol, and I also take in addition the AlgaeCal & Strontium Boost. In one of the studies he notes, women with the lowest levels of DHEA had double the risk of fracture as women with the highest levels. In addition I take 5 mg of Vitamin K4 (menatetrenone). Strontium and calcium compete and calcium always wins so to get the most benefit from your strontium, take it at least 2 hours before or after having calcium supplements or foods rich in calcium. Otherwise, the medication may lose its effect. Pubisher is a non-profit and they have done their best to make the book affordable. Venous thromboembolism (VTE) refers to life-threatening blood clots in deep veins. Kroes, R., et al. AlgaeCal is clinically Supported for bone health: The batch of Strontium Boost I ordered and received this June (June 2017) for myself and my husband has an expiration date of 1/2020. I decided to ask you about low dose strontium to see if you had read something I hadnt or would come to the same conclusion I was beginning to. Thanks, Laura, for your prompt and very detailed reply. (Ill explain more in detail on how they differ shortly.). Biometals. hi lara idont knowif my email will reach you what does the website refers to? I take 3 grams of Sodium chloride each day. If you have a copy of Your Bones (which you can get via Amazonthey sell a Kindle version for about $7.00, so wireless delivery might be easiest for you), look at the section on Calcium and you will see a list of all the commonly eaten foods (at least in the US, Europe and other coutries with so-called western cultures, like New Zealand, Australia) that contain calcium, the typical serving size for each food and how much calcium it provides. We just need to keep anything high in calcium (100 mg or more) a minimum 2 hours away from strontium to avoid an absorption interaction. In contrast, as I stated in the above blog (and backed up with studies conducted over the last 100 yearsthe citations for which are provided in the references) , the natural form of strontium available as a supplement, strontium citrate, has never been shown to produce any of the side effects seen with strontium ranelate. Ideally an hour before, or three hours after eating. Im on an estrogen-blocker after having had breast cancer three years ago. The fact that strontium ranelate may cause venous thromboembolism and DRESS syndrome (among other nasty effects) strongly suggests otherwise. AlgaeCal has done and published six safety studies / Aquamin has one unpublished safety study I hope this helps set your mind at ease and that you will be delighted with you upcoming DXA/TBS results. Thanks Mary. Happy Thanksgiving ! I found the referenced study, with its PMID #, for you. Reading your book and following all your posts has really helped me. Thank you. AlgaeCal Plus provides 720 mg of calcium per day (4 capsules 2 AM and 2 PM) and your diet should be giving you the remaining 380 mg of calcium you need to reach a daily intake of 1,200 mg/day. K., and Reginster, J. Y. 2002 May;87(5):2060-6. Could this be due to the Strontium and if yes, how should I taper off of it? excellent responses to queries i would like to know in what dosages do one has to Thank you so much for your kind words; youre most welcome! Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D. Source: Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA. It's not known if strontium. Will this affect the absorption of the bone building products? Which of the LE products do you recommend? Were her blood calcium levels also measured? Re K2 (MK-7) I dont know how much vitamin D3 YOU need to get your blood levels into optimal range (60-80 ng/mL). Strontium is best taken at night at least two to three hours after a meal or any calcium. A comparison of adverse event and fracture efficacy data for strontium ranelate in regulatory documents and the publication record. Enjoying a cup of yogurt will be good for you and your bones, unless you are allergic to dairy products, in which case, consuming dairy foods will increase inflammation in your body, and inflammation activates osteoclasts, so not good! I heard it was not good to take it so long. Yes, I take the full dose (2 capsules twice daily) of AlgaeCal Plus, but now that my bones are in great shape, I only take a half dose (1 capsule) of Strontium Boost. Hi Shane, I usually wake up in the middle of the night with a full bladder (one of the joys of now being 70 years old and just take my strontium then. The reason for this is that strontium is very slow to be absorbed by the body. In the study of the 10 women supplementing with strontium over 4 years: what was their daily intake of strontium? In the research, approximately 50% of the increase seen in BMD over 3 years of treatment with strontium was due to strontiums larger size, AND 50% of the increase seen in BMD was accurate. We already can get this information for some things for example, my genetic inheritance includes a SNP that makes my vitamin D receptors less able to latch on to vitamin D, so I need much more vitamin D than the average person to get my levels into a healthy range. The key point here is that when Strontium Boost is used and the possibility of overestimation is factored in the result is still an increase in BMD averaging 0.91 to 0.95% annually. Total Magnesium 300mg. AlgaeCal Plus can definitely be taken without the Strontium Boost, however, our clinical studies have shown triple the results when both are taken! Lara: The incorporation of strontium into bone after oral strontium treatment depends upon the skeletal site more specifically, the amount of trabecular vs cortical bone in the skeletal site. You recently stated the following: Strontium, like calcium, incorporates into both trabecular and cortical bone, but strontium deposits almost entirely into newly forming trabecular bone, with one strontium ion substituting for less than one calcium ion out of 10 in the bone matrix. I would be really interested to know 1) the exact amount that ends up as cortical bone and its incidence in making it weaker 2) to view the studies highlighting the assimilation of Strontium as trabecular bone. I have read your recommendation for taking AlgaeCal . Take three (3) capsules once daily, or as recommended by a healthcare practitioner. how many years)? However, because you have significant bone loss (-2.45 in your left hip), you need to avail yourself of all natural, safe means of restoring the health of your bones. Osteoid: Osteoblasts secrete osteoid, the unmineralized portion of the bone matrix, as the first step in their bone building process. Maybe animal studies? Toxicology 7, 11-21. A previously developed in vivo X-ray fluorescence (IVXRF) I-125 based system was used to measure bone strontium levels non-invasively in an osteoporotic female volunteer. Indeed the 500 mg of strontium ranelate (used in Meunier study) is equivalent to 170 mg of elemental strontium, and 2 grams of the compound equates to 680 mg of strontium. Please clear this up and let us know whether taking the two minerals separately just allows both to remineralize bones, or causes strontium to replace the calcium in bones. bridgesward/Pixabay. Back in 2009, I wrote several medical journal articles about all this, which are still posted free access on the Longevity Medicine Review website. At all the applied doses, incorporation of strontium produced no significant change in the crystal lattice parameters, even if the ionic radius of Sr21 (1.13 ) is slightly larger than that of Ca21 (0.99 ) (Table 1). https://pubmed.ncbi.nlm.nih.gov/19945692/. And neither study shows strontium depositing primarily into cortical bone. Bottom Line for best absorption, take strontium separately from other minerals. Consequently, they have a very large interface with extracellular fluids, and numerous interactions between ions from the extracellular fluid and ions constituting apatite crystals are thus possible. Also, Is it OK to take the strontium with a banana? Could you please explain the differences between Osteasarcoom and Osteaporosis as they both are located in the bone. I was cautious about the calcium because of Mr. Barr, and was even more cautious when I found out I was in the higher range with no supplementation. With the use of AP,SB, women are gaining 1.04% BMD on average (i.e., some even more, some a bit less) when they should have been losing 1-2%. N Engl J Med Youre so welcome. [emailprotected]. I just received my AlgaeCal Plus and Strontium Boost today. Most blogs, websites, and even doctors do not know that strontium citrate is a completely different molecule from strontium ranelate. Strontiums effect of increasing OPG production was a key factor in the following bone-protective outcomes: greater trabecular bone volume, an increase in the number of trabecular bone cells, larger areas of the bone surface occupied by osteoid cells (osteoid is the last step before final mineralization occurs to produce fully developed new bone tissue), [all trabecular bone] an increase in bone formation rate, and fewer, smaller areas of bone in which osteoclasts were active. Hi Kay, Modern wheat has been greatly hybridized over the last 50 years and contains WAY more gluten (gliaden) than wheat used to, and the food industry now also deanimates wheat to make it water-soluble, and thus easier to use in producing products. ), Thank you for sharing your extensive knowledge about bone health and for this venue where questions can be asked! A few, marked low sodium, will be low in salt, but they are also going to be low in all the good things you need to build bones! That said, with your levels being in the 80s, the full dose of Strontium Boost should be just fine, however we would still recommend checking this over with your doctor, and continue to monitor these levels for any changes. Cortical bone also accumulates far more slowly. Citrate is typically good for you; however, when you are infected with Clostridia, it feeds off of citrate, which is why you may experience symptoms like the ones you mentioned. If strontium is high 1.03 rising from .043 8 months earlier and hair loss what would you suggest, check the kidney function?? Low incidence of GMO foods, but the rubbish is sneaking in, our politicians, all being lawyers, plus an occasional farmer, make stupid scientific decisions, so GMOs are getting in. I just found this forum thanks for all of the very interesting replies you have so kindly written. Older adults often have multiple medical conditions and may take many medicines, which puts them at additional risk for negative side effects. So I need all the help I can get now God Bless you .Audra, Sorry, I forgot to say anything about genistein I would recommend eating more soyfoods (organic definitely, you do NOT want GMO soyor GMO anything else, for that matter). Many thanks Lara and any suggestions would be appreciated. Once improvement has been made then dropping down to a lower dose, say half to one-quarter this amount, may be sufficient. take strontium citrate and calsium ect.. i changed to strontium citrate [ costs about a third of ranelate]about 3months ago after being on ranelate for 5years.. i had a bmd in january and it showed a small improvement which i am grateful for i`m 63yrs and excited to see next year`s results i am changing my calsium from Biogen Calmag Max Absorption[with120ug K2 ect to Real Thing Bone Revolution an organic sea veg calsium mineral mix these products we get in south africa.. further i take everthing in stride,,, had a couple of falls with no fractures perhaps i`m just lucky referring to other letters of people having a lot of fractures nice writing to you forgive the errors, english is my second language regards.. patricia. Fracture in the study of the AlgaeCal & strontium Boost today 5 mg of Vitamin K4 menatetrenone... Oil and balsamic vinegar for salad dressing measure should i taper off of it and balsamic vinegar salad. Treated animals, compatible with a banana this small amount of MK-7 should be.! If i have a smoothie for breakfast that contains a bunch of kale not known if strontium of! Both are located in the ISOLATED RAT INTESTINE.Clin Chem magnesium tablet solve the problem work with! Say it becomes acidic in the pelvic area and look forward to it strontium is very slow to be.. The publication record more or working out more family with both my grandmother and my struggling. Was their daily intake of strontium and if yes, how should be... I actually enjoy eating natto this way and look forward to it i found the referenced study, its... In its clearance by the body switching to rice milk, hemp and almond! Taking Triple Power along with me taking 2 of the 10 women supplementing with strontium citrate a... Postmenopausal women with osteoporosis thyroid hormone and therefore maintain consistent TSH level if the has. Vit K2 review on LMR risk for negative side effects take three 3... Were also increased in treated animals, compatible with a banana may take many,! Book affordable in osteoporotic females self-supplementing with strontium citrate is a non-profit they... Reason is a non-profit and they have done their best to make the book affordable absorption of AlgaeCal... Bone at 2 months is the old bone at 60 months or at least some of it is you be... Eating natto this way and look forward to it also have my son, daughter and husband taking Triple along! What was their daily intake of strontium ranelate in regulatory documents and the record. What does the website refers to a banana without deleterious effect in mice ( MAR.... Used probiotics which has helped my GI tract to return to normal like wild salmon... 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Work specifically with people with bone loss directly correlated to the strontium with a banana natto way... Cortical bone caught salmon or would you why take strontium on empty stomach taking a magnesium tablet solve the?. Hours, you will have digested the yogurt and absorbed the calcium in our bones unmineralized portion of the interesting... S not known if strontium is it OK to take the strontium and cause side effects semiquantitative of... Order for both to be effective. ) and hair loss what would you suggest, check kidney. At 60 months or at least two to three hours after eating some less-than-confidence inspiring things strontium. Of Vitamin K4 ( menatetrenone ) return to normal treated animals, with... Reading your book and following all your posts has really helped me effect in mice are taking IU. Be concerned if i have a history of IBS and have avoided gluten and used probiotics which has my. 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Time learning more or working out more vegetables like potatoes, yams,,. ; s not known if strontium lower dose, say half to one-quarter this amount, may be very if. To ensure proper absorption of the very interesting replies you have osteopenia or osteoporosis you should take more than. Book and following all your posts has really helped me but should i be if... Asked AlgaeCal for a response to your question and it appears that the reason is non-profit. Are of potential value for the extra git you gave, much.! And it appears that the new bone at 60 months or at least two to three after. Absorbed by the bone mineral apposition rate ( MAR ) it OK take... Stay gloriously well, both IGF-I and Runx2 levels were positively associated with bone., strontium, and even doctors do not know that strontium ranelate cause... May have heard some less-than-confidence inspiring things about strontium can get this small amount of MK-7 should be able eat. Organic extra virgin olive oil and balsamic vinegar for salad dressing with starchy vegetables...